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Business Plan

Alginar business plan open PDF

Biotechnological production of a drug for the treatment of cancer

1. Description of the product and the necessary funding for implementation

Production of a safe preparation from a strain of black Antarctic yeast "Nadsoniella nigra var. Hesuelica" for the treatment of various types of cancer.

Scientific rationale: we studied more than 30,000 pages of text documents on working with melanin by the Soviet biochemist, Ph.D. Svetlana Lyakh, who has devoted more than 30 years of her scientific career to the study and work with black Antarctic yeast nigra var. Hesuelica . The drug was given the name "AstroMelanin". Subsequently, Svetlana Lyakh received confirmation of the very high antioxidant activity and anticancer properties of this drug. In addition, as a result of research, a positive effect was obtained on a number of other diseases, such as type II diabetes mellitus, gastric ulcer, and bronchial asthma. With its very high antioxidant activity of 10-16 spin / mg, the drug can also be used to increase immunity.

The development received positive feedback and support from the heads of three leading oncological centers in Russia, who assessed the drug as promising and reflecting the latest methods in cancer treatment.

For 2 years of work, we have completely recreated the laboratory technology for the production of melanin from the strain of black Antarctic yeast Nadsoniella nigra var. Hesuelica.

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2. Trouble in the world

According to WHO estimates, cancer is the leading cause of death in the world. According to GLOBOCAN, in 2020, 19.3 million new cases of cancer were registered worldwide and more than 11 million people died.

The annual increase is between 3 and 5%, and by 2040 it is expected to grow to 28.4 million new cases per year.

3 . Economic overview

Depending on the drug, treatment costs can range from $150,000 with Keytruda to $450,000 with Kimriah for a year of treatment. However, these drugs do not give guarantees for a complete cure, and new foci of the disease may appear after a while. All drugs have a large number of side effects on the body.

According to US National Library of Medicine National institutes of Health 2017:

the average cost of developing a single drug in 2017 was $793 million

average development time per drug is 7.3 years

average profit from the sale of one drug per year $330 million

Expenditure on medicines used to treat cancer patients has more than tripled in 10 years:

2011 total spending $56 billion

2021 total spending $187 billion

Over the next 5 years, the market is expected to grow to $280-$300 billion.

Cancer drug sales, according to S&P Global market Intelligence for 2020:

Keytruda - $14.38 billion

Eliquis - $14.12 billion

Revlimid - $12.1 billion

Eylea - $10.7 billion

Imbruvica - $9.4 billion

4. Potential buyer

At the initial stage of sale, the drug will be registered as a dietary supplement, and it will be sold through pharmacy chains and online platforms.

We already have an interested partner (a Russian manufacturing company with extensive experience in the production, sale and promotion of dietary supplements), ready to promote and sell our drug.

The next stage is clinical trials, as a result of which the drug will be of interest to medical institutions and clinics involved in the treatment of oncology, as well as individuals who need effective and safe treatment.

There is already a demand for the drug at this stage, since it has a rather long history and positive results of use.

5. Why people will buy from us

Our drug is non-toxic and completely safe for the body, unlike other oncological drugs used. Our drug is recommended for both treatment and prevention, due to the absence of any harmful side effects on the body.

We are the exclusive and sole manufacturer of this drug, with full rights to the full production technology.

Stage 1. Launch of small production with the involvement of a company for outsourcing the cultivation of yeast culture.


Start production and work out the technology for the industrial production of the drug

Register the drug as a dietary supplement

Start selling dietary supplement

Collect statistics and reviews on the use of the drug

Apply for a patent for drug development

Create market demand

Production calculation:

Production capacity: 1 kg of finished products per month

1 kg of melanin = 500 monthly courses of the drug

Minimum initial selling price: preliminary $300 for a monthly course

Profit for 1 month: 500 x $300 = $150 000

Profit per year: $150 000 x 12 = $1 800 000

Production is planned to open in the special economic zone "Technopolis Moscow"


Purchase of equipment, launch of production, payroll, marketing: $280 000

Stage 2. Organization of the full production cycle


Start a full production cycle. Prepare for preclinical and clinical studies, collect data on the results of the use of the drug.

Production capacity: 4 kg of finished product per month

4 kg of finished products per month = 2000 monthly courses of the drug

Profit for 1 month: 2000 x $300 = $600 000

Profit per year: $600 000 x 12 = $7 200 000


Director, accountant, technical director, chief engineer, supply manager, biotechnologist, equipment operator, laboratory assistant on duty, mechanic on duty, electrician on duty (repair personnel), wastewater treatment plant operator, EPR spectrum operator.

                               Cost estimate for 2 years

Purchase, installation, launch of equipment: $4 800 000

Building construction: $1 600 000 - $1 900 000

Purchase of office equipment and software: $18 000

Purchase of raw materials for production: $200 000

Purchase of reagents and consumables: $60 000

Maintenance and service of equipment: $30 000

Overhead costs, wages, business expenses: $950 000

Promotion, marketing: $100 000

Total: $8 058 000

Starting from the second year of operation, production is fully paid off and we receive a net profit.

Stage 3. Conducting preclinical and clinical studies

The goal is to convert dietary supplement into drug.

Based on the production base and experience in the use of the drug, preclinical and clinical studies can be started. This will create an increased demand for products and recommendations from physicians for use by patients. A positive result of the research will give a huge potential for the application of products in the world market. Based on the positive results of studies, the price of the drug can be increased by 2 or more times, since the drug will receive the status of a drug with an effect confirmed by clinical studies.

Terms of testing: 3-4 years.

Cost: $2.5-$3 million

Stage 4. Scaling production

Based on the results of preclinical and clinical studies, with a positive outcome, a decision is made to increase the production capacity.

Since the global demand for drugs for the treatment of oncology is constantly growing, and our drug is also safe for the body, has no side and harmful effects, the demand for it will far exceed the supply.

Conducting an IPO to raise additional funds in order to increase production capacity.

In the future, the sale of the company or a merger with a large pharmaceutical company is possible.

2004 - Pfizer buys cancer drug from Aventis for $620 million

2016 - Pfizer bought out Medivation (manufacturer of cancer drugs ) $14 billion

2018 – GlaxSmithKline bought out TESARO (manufacturer of cancer drugs ) $5.1 billion

2019 - Pfizer bought out Array BioPharma (manufacturer of cancer drugs ) $11.4 billion